6XIG

X-ray crystal structure of MqnE from Pedobacter heparinus

Summary for 6XIG

• Entry DOI: 10.2210/pdb6xig/pdb
• Descriptor: Aminodeoxyfutalosine synthase, IRON/SULFUR CLUSTER, D(-)-TARTARIC ACID, ... (4 entities in total)
• Functional Keywords: iron-sulfur cluster, radical sam, menaquinone biosynthesis, biosynthetic protein
• Biological source: Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3)
• Total number of polymer chains: 2
• Total formula weight: 99204.21

Authors

Grove, T.L.,Bonanno, J.B.,Almo, S.C. (deposition date: 2020-06-19, release date: 2020-07-15, Last modification date: 2024-03-06)

• Primary citation: Carl, A.G.,Harris, L.D.,Feng, M.,Nordstrom, L.U.,Gerfen, G.J.,Evans, G.B.,Silakov, A.,Almo, S.C.,Grove, T.L.; Narrow-Spectrum Antibiotic Targeting of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis.; Biochemistry, 59:2562-2575, 2020; PubMed: 32627538; DOI: 10.1021/acs.biochem.0c00070

Experimental method

X-RAY DIFFRACTION (1.59 Å)