6XC4

Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC12.3

Summary for 6XC4

• Entry DOI: 10.2210/pdb6xc4/pdb
• Related: 6XC2 6XC3
• Descriptor: Spike protein S1, CC12.3 heavy chain, CC12.3 light chain, ... (5 entities in total)
• Functional Keywords: antibody, sars-cov-2, coronavirus, spike, immune system, immune system-viral protein complex, immune system/viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 6
• Total formula weight: 146251.34

Authors

Yuan, M.,Liu, H.,Wu, N.C.,Zhu, X.,Wilson, I.A. (deposition date: 2020-06-08, release date: 2020-07-08, Last modification date: 2023-10-18)

• Primary citation: Yuan, M.,Liu, H.,Wu, N.C.,Lee, C.D.,Zhu, X.,Zhao, F.,Huang, D.,Yu, W.,Hua, Y.,Tien, H.,Rogers, T.F.,Landais, E.,Sok, D.,Jardine, J.G.,Burton, D.R.,Wilson, I.A.; Structural basis of a shared antibody response to SARS-CoV-2.; Science, 369:1119-1123, 2020; PubMed: 32661058; DOI: 10.1126/science.abd2321

Experimental method

X-RAY DIFFRACTION (2.341 Å)