6X93
Interleukin-10 signaling complex with IL-10RA and IL-10RB
Summary for 6X93
Entry DOI | 10.2210/pdb6x93/pdb |
EMDB information | 22098 |
Descriptor | Interleukin-10, Interleukin-10 receptor subunit alpha, Interleukin-10 receptor subunit beta (3 entities in total) |
Functional Keywords | il-10, cytokine, receptor, il-10ra, il-10rb, signaling |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 133540.54 |
Authors | Saxton, R.A.,Tsutsumi, N.,Gati, C.,Garcia, K.C. (deposition date: 2020-06-02, release date: 2021-03-17, Last modification date: 2021-03-31) |
Primary citation | Saxton, R.A.,Tsutsumi, N.,Su, L.L.,Abhiraman, G.C.,Mohan, K.,Henneberg, L.T.,Aduri, N.G.,Gati, C.,Garcia, K.C. Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10. Science, 371:-, 2021 Cited by PubMed: 33737461DOI: 10.1126/science.abc8433 PDB entries with the same primary citation |
Experimental method |
Structure validation
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