6X6E

Glucocorticoid Receptor DNA binding domain in complex with methylated precursor for a modern recognition element (methylated pre-GBS)

6X6E の概要

• エントリーDOI: 10.2210/pdb6x6e/pdb
• 分子名称: Glucocorticoid receptor, DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*GP*GP*AP*GP*(5CM)P*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*AP*AP*CP*GP*CP*TP*CP*(5CM)P*GP*TP*TP*CP*TP*G)-3'), ... (5 entities in total)
• 機能のキーワード: gr, pre-gbs, dna binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 28096.65

構造登録者

Liu, X.,Ortlund, E.A. (登録日: 2020-05-28, 公開日: 2021-06-02, 最終更新日: 2023-10-18)

• 主引用文献: Liu, X.,Weikum, E.R.,Tilo, D.,Vinson, C.,Ortlund, E.A.; Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element.; Nucleic Acids Res., 49:8923-8933, 2021; PubMed: 34289059; DOI: 10.1093/nar/gkab605

実験手法

X-RAY DIFFRACTION (2 Å)