6X5H

Human Alpha-1,6-fucosyltransferase (FUT8) bound to GDP

6X5H の概要

• エントリーDOI: 10.2210/pdb6x5h/pdb
• 分子名称: Alpha-(1,6)-fucosyltransferase, GUANOSINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: glycosyl transferase, fucosyl transferase, gt-b fold, inverting, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 249699.53

構造登録者

Kadirvelraj, R.,Wood, Z.A. (登録日: 2020-05-26, 公開日: 2020-10-07, 最終更新日: 2023-10-18)

• 主引用文献: Boruah, B.M.,Kadirvelraj, R.,Liu, L.,Ramiah, A.,Li, C.,Zong, G.,Bosman, G.P.,Yang, J.Y.,Wang, L.X.,Boons, G.J.,Wood, Z.A.,Moremen, K.W.; Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases.; J.Biol.Chem., 295:17027-17045, 2020; PubMed: 33004438; DOI: 10.1074/jbc.RA120.014625

実験手法

X-RAY DIFFRACTION (2.25 Å)