6WYO

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 (CD1) H82F F202Y double mutant complexed with Trichostatin A

Summary for 6WYO

Entry DOI	10.2210/pdb6wyo/pdb
Descriptor	Histone deacetylase 6, ZINC ION, POTASSIUM ION, ... (5 entities in total)
Functional Keywords	histone deacetylase, hydrolase, metalloprotein
Biological source	Danio rerio (Zebrafish)
Total number of polymer chains	2
Total formula weight	85047.25
Authors	Osko, J.D.,Christianson, D.W. (deposition date: 2020-05-13, release date: 2020-09-02, Last modification date: 2023-10-18)
Primary citation	Osko, J.D.,Christianson, D.W. Binding of inhibitors to active-site mutants of CD1, the enigmatic catalytic domain of histone deacetylase 6. Acta Crystallogr.,Sect.F, 76:428-437, 2020 Cited by PubMed: 32880591 DOI: 10.1107/S2053230X20010250 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.30000278768 Å)

Structure validation