6WXU

CryoEM structure of mouse DUOX1-DUOXA1 complex in the dimer-of-dimer state

6WXU の概要

• エントリーDOI: 10.2210/pdb6wxu/pdb
• EMDBエントリー: 21963
• 分子名称: Dual oxidase 1, Dual oxidase maturation factor 1, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: membrane protein, protein complex, nadph oxidase, ros production
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 437489.54

構造登録者

Sun, J. (登録日: 2020-05-12, 公開日: 2020-09-02, 最終更新日: 2021-03-17)

• 主引用文献: Sun, J.; Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation.; Nat.Struct.Mol.Biol., 27:1086-1093, 2020; PubMed: 32929281; DOI: 10.1038/s41594-020-0501-x

実験手法

ELECTRON MICROSCOPY (2.7 Å)