6WX8
SOX2 bound to Importin-alpha 3
Summary for 6WX8
Entry DOI | 10.2210/pdb6wx8/pdb |
Descriptor | Importin subunit alpha-3, Transcription factor SOX-2, SULFATE ION, ... (4 entities in total) |
Functional Keywords | nuclear protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 123221.99 |
Authors | Bikshapathi, J.,Stewart, M.,Forwood, J.K.,Aragao, D.,Roman, N. (deposition date: 2020-05-10, release date: 2020-10-28, Last modification date: 2023-10-25) |
Primary citation | Jagga, B.,Edwards, M.,Pagin, M.,Wagstaff, K.M.,Aragao, D.,Roman, N.,Nanson, J.D.,Raidal, S.R.,Dominado, N.,Stewart, M.,Jans, D.A.,Hime, G.R.,Nicolis, S.K.,Basler, C.F.,Forwood, J.K. Structural basis for nuclear import selectivity of pioneer transcription factor SOX2. Nat Commun, 12:28-28, 2021 Cited by PubMed: 33397924DOI: 10.1038/s41467-020-20194-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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