6WX8

SOX2 bound to Importin-alpha 3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Importin subunit alpha-3	polymer	459	50325.8	2	UniProt (O00629) Pfam (PF01749) Pfam (PF16186) Pfam (PF00514)	Homo sapiens (Human)	Importin alpha Q1,Qip1,Karyopherin subunit alpha-4
2	B, D (B, D)	Transcription factor SOX-2	polymer	90	11045.0	2	UniProt (P48431) Pfam (PF00505)	Homo sapiens (Human)
3	E, F, G, H, I (A, B, D)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
4	J, K, L, M (A, B, C, D)	water	water		18.0	227	Chemie (HOH)

Sequence modifications

A, C: 64 - 521 (UniProt: O00629)

PDB	External Database	Details
Ser 63	-	expression tag

B, D: 39 - 127 (UniProt: P48431)

PDB	External Database	Details
Ser 38	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	122741.7
Non-Polymers*	Number of molecules	5
	Total formula weight	480.3
All*	Total formula weight	123222.0

*Water molecules are not included.