6WKW

EM structure of CtBP2 with a minimal dehydrogenase domain of CtBP2

Summary for 6WKW

Entry DOI	10.2210/pdb6wkw/pdb
EMDB information	21811
Descriptor	C-terminal-binding protein 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (2 entities in total)
Functional Keywords	transcriptional corepression, cancer, gene repression, metabolic sensor, gene regulation
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	149136.56
Authors	Jecrois, A.M. (deposition date: 2020-04-17, release date: 2020-12-02, Last modification date: 2024-03-06)
Primary citation	Jecrois, A.M.,Dcona, M.M.,Deng, X.,Bandyopadhyay, D.,Grossman, S.R.,Schiffer, C.A.,Royer Jr., W.E. Cryo-EM structure of CtBP2 confirms tetrameric architecture. Structure, 29:310-, 2021 Cited by PubMed: 33264605 DOI: 10.1016/j.str.2020.11.008 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation