6WJT

2.0 Angstrom Resolution Crystal Structure of Nsp16-Nsp10 Heterodimer from SARS-CoV-2 in Complex with S-Adenosyl-L-Homocysteine

6WJT の概要

• エントリーDOI: 10.2210/pdb6wjt/pdb
• 関連するPDBエントリー: 6w75
• 分子名称: 2'-O-methyltransferase, Non-structural protein 10, SODIUM ION, ... (7 entities in total)
• 機能のキーワード: structural genomics, center for structural genomics of infectious diseases, csgid, nsp16, nsp10, complex, viral protein, s-adenosyl-l-homocysteine
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 99080.15

構造登録者

Minasov, G.,Shuvalova, L.,Rosas-Lemus, M.,Kiryukhina, O.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2020-04-14, 公開日: 2020-04-22, 最終更新日: 2023-10-18)

• 主引用文献: Rosas-Lemus, M.,Minasov, G.,Shuvalova, L.,Inniss, N.L.,Kiryukhina, O.,Brunzelle, J.,Satchell, K.J.F.; High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design.; Sci.Signal., 13:-, 2020; PubMed: 32994211; DOI: 10.1126/scisignal.abe1202

実験手法

X-RAY DIFFRACTION (2 Å)