6WIT
Crystal structure of NHP D15.SD7 Fab in complex with 16055 V1V2 1FD6 scaffold
Summary for 6WIT
Entry DOI | 10.2210/pdb6wit/pdb |
Related | 6VJN 6WAS |
Descriptor | NHP GN1-SD7 Fab Heavy Chain, NHP GN1-SD7 Fab Light Chain, 16055 V1V2 1FD6 Scaffold, ... (6 entities in total) |
Functional Keywords | fab, hiv, v1v2, complex, antibody, scaffold, antiviral protein-immune system complex, antiviral protein/immune system |
Biological source | Macaca mulatta (Rhesus monkey) More |
Total number of polymer chains | 6 |
Total formula weight | 125063.11 |
Authors | Liban, T.,Aljedani, S.,Rodarte, J.,Pancera, M. (deposition date: 2020-04-10, release date: 2021-04-14, Last modification date: 2023-10-18) |
Primary citation | Aljedani, S.S.,Liban, T.J.,Tran, K.,Phad, G.,Singh, S.,Dubrovskaya, V.,Pushparaj, P.,Martinez-Murillo, P.,Rodarte, J.,Mileant, A.,Mangala Prasad, V.,Kinzelman, R.,O'Dell, S.,Mascola, J.R.,Lee, K.K.,Karlsson Hedestam, G.B.,Wyatt, R.T.,Pancera, M. Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17:e1009543-e1009543, 2021 Cited by PubMed: 34559844DOI: 10.1371/journal.ppat.1009543 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.79 Å) |
Structure validation
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