6WG4

Crystal structure of human SMC1-SMC3 hinge domain heterodimer in south-open conformation

Summary for 6WG4

• Entry DOI: 10.2210/pdb6wg4/pdb
• Related: 6WG3
• Descriptor: Structural maintenance of chromosomes protein, Structural maintenance of chromosomes protein 3 (3 entities in total)
• Functional Keywords: atpase, dna-binding protein, genome organization, sister chromatid cohesion, transcription regulation, cell cycle
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 42923.54

Authors

Shi, Z.B.,Yu, H. (deposition date: 2020-04-04, release date: 2020-05-20, Last modification date: 2023-10-18)

• Primary citation: Shi, Z.,Gao, H.,Bai, X.C.,Yu, H.; Cryo-EM structure of the human cohesin-NIPBL-DNA complex.; Science, 368:1454-1459, 2020; PubMed: 32409525; DOI: 10.1126/science.abb0981

Experimental method

X-RAY DIFFRACTION (2.31 Å)