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6WG4

Crystal structure of human SMC1-SMC3 hinge domain heterodimer in south-open conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AStructural maintenance of chromosomes proteinpolymer17920161.41UniProt (G8JLG1)
Pfam (PF06470)
UniProt (by SIFTS) (Q14683)
In PDB
Homo sapiens (Human)
2BStructural maintenance of chromosomes protein 3polymer20122762.11UniProt (Q9UQE7)
Pfam (PF06470)
In PDB
Homo sapiens (Human)SMC-3,Basement membrane-associated chondroitin proteoglycan,Bamacan,Chondroitin sulfate proteoglycan 6,Chromosome-associated polypeptide,hCAP
3waterwater18.0209Chemie (HOH)
Sequence modifications
A: 499 - 675 (UniProt: G8JLG1)
PDBExternal DatabaseDetails
Gly 497-expression tag
Pro 498-expression tag
B: 493 - 685 (UniProt: Q9UQE7)
PDBExternal DatabaseDetails
Gly 485-expression tag
Pro 486-expression tag
Leu 487-expression tag
Gly 488-expression tag
Ser 489-expression tag
Gly 490-expression tag
Arg 491-expression tag
Pro 492-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42923.5
All*Total formula weight42923.5
*Water molecules are not included.

221051

PDB entries from 2024-06-12

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