6WG4
Crystal structure of human SMC1-SMC3 hinge domain heterodimer in south-open conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Structural maintenance of chromosomes protein | polymer | 179 | 20161.4 | 1 | UniProt (G8JLG1) Pfam (PF06470) UniProt (by SIFTS) (Q14683) | Homo sapiens (Human) | |
| 2 | B (B) | Structural maintenance of chromosomes protein 3 | polymer | 201 | 22762.1 | 1 | UniProt (Q9UQE7) Pfam (PF06470) | Homo sapiens (Human) | SMC-3,Basement membrane-associated chondroitin proteoglycan,Bamacan,Chondroitin sulfate proteoglycan 6,Chromosome-associated polypeptide,hCAP |
| 3 | C, D (A, B) | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence modifications
A: 499 - 675 (UniProt: G8JLG1)
B: 493 - 685 (UniProt: Q9UQE7)
| PDB | External Database | Details |
|---|---|---|
| Gly 497 | - | expression tag |
| Pro 498 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 485 | - | expression tag |
| Pro 486 | - | expression tag |
| Leu 487 | - | expression tag |
| Gly 488 | - | expression tag |
| Ser 489 | - | expression tag |
| Gly 490 | - | expression tag |
| Arg 491 | - | expression tag |
| Pro 492 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42923.5 | |
| All* | Total formula weight | 42923.5 |
