6WDU

The external aldimine form of the Salmonella thypi wild-type tryptophan synthase in open conformation showing multiple side chain conformations for the residue beta Q114 and sodium ion at the metal coordination site. One of the beta-Q114 rotamer conformations allows a hydrogen bond to form with the PLP oxygen at the position 3 in the ring.

6WDU の概要

• エントリーDOI: 10.2210/pdb6wdu/pdb
• 関連するPDBエントリー: 6dz4 6dzo
• 分子名称: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 1,2-ETHANEDIOL, ... (8 entities in total)
• 機能のキーワード: lyase-inhibitor, protein complex, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 73800.52

構造登録者

Hilario, E.,Fan, L.,Dunn, M.F.,Mueller, L.J. (登録日: 2020-04-01, 公開日: 2021-03-10, 最終更新日: 2023-10-18)

• 主引用文献: Hilario, E.,Fan, L.,Dunn, M.F.,Mueller, L.J.; The external aldimine form of the Salmonella thypi wild-type tryptophan synthase in open conformation showing multiple side chain conformations for the residue beta Q114 and sodium ion at the metal coordination site. One of the beta-Q114 rotamer conformations allows a hydrogen bond to form with the PLP oxygen at the position 3 in the ring.; To be Published,

実験手法

X-RAY DIFFRACTION (1.4 Å)