6DZO
Crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-Q114A with 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site, and (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine at the beta-site
Summary for 6DZO
Entry DOI | 10.2210/pdb6dzo/pdb |
Related | 4HN4 4HPX 6DZ4 |
Descriptor | Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... (9 entities in total) |
Functional Keywords | q114a, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) More |
Total number of polymer chains | 2 |
Total formula weight | 73378.57 |
Authors | Hilario, E.,Dunn, M.F.,Mueller, L.J.,Fan, L. (deposition date: 2018-07-05, release date: 2019-07-10, Last modification date: 2023-10-11) |
Primary citation | Hilario, E.,Dunn, M.F.,Mueller, L.J.,Fan, L. Crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-Q114A with 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site, and (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine at the beta-site To be Published, |
Experimental method | X-RAY DIFFRACTION (1.64 Å) |
Structure validation
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