6W9E
Crystal Structure of Human CDK9/cyclinT1 in complex with MC180295
Summary for 6W9E
Entry DOI | 10.2210/pdb6w9e/pdb |
Descriptor | Cyclin-dependent kinase 9, Cyclin-T1, (4-amino-2-{[(1S,2S,4R)-bicyclo[2.2.1]heptan-2-yl]amino}-1,3-thiazol-5-yl)(2-nitrophenyl)methanone, ... (6 entities in total) |
Functional Keywords | cdk9, cyclin t1, mc180295, complex, transcriptional regulator, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 69736.17 |
Authors | |
Primary citation | Kirubakaran, P.,Morton, G.,Zhang, P.,Zhang, H.,Abou-Gharbia, M.,Issa, J.,Wu, J.,Childers, W.,Karanicolas, J. Comparative Modeling of CDK9 Inhibitors to Explore Selectivity and Structure-Activity Relationships To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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