6W6Q
WT HTLV-1 Protease in Complex with Darunavir (DRV)
Summary for 6W6Q
Entry DOI | 10.2210/pdb6w6q/pdb |
Descriptor | HTLV-1 Protease, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE (3 entities in total) |
Functional Keywords | htlv, protease, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human T-cell leukemia virus type I |
Total number of polymer chains | 2 |
Total formula weight | 25680.82 |
Authors | Lockbaum, G.J.,Henes, M.,Kosovrasti, K.,Nalivaika, E.A.,Ali, A.,KurtYilmaz, N.,Schiffer, C.A. (deposition date: 2020-03-17, release date: 2021-03-17, Last modification date: 2023-10-18) |
Primary citation | Lockbaum, G.J.,Henes, M.,Kosovrasti, K.,Nalivaika, E.A.,Ali, A.,KurtYilmaz, N.,Schiffer, C.A. To Be Determined To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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