6W1S

Atomic model of the mammalian Mediator complex

6W1S の概要

• エントリーDOI: 10.2210/pdb6w1s/pdb
• EMDBエントリー: 21514
• 分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 15, Mediator of RNA polymerase II transcription subunit 16, ... (25 entities in total)
• 機能のキーワード: mouse mediator, complex, gene regulation
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 25
• 化学式量合計: 975066.81

構造登録者

Zhao, H.,Young, N.,Asturias, F. (登録日: 2020-03-04, 公開日: 2021-03-10)

• 主引用文献: El Khattabi, L.,Zhao, H.,Kalchschmidt, J.,Young, N.,Jung, S.,Van Blerkom, P.,Kieffer-Kwon, P.,Kieffer-Kwon, K.R.,Park, S.,Wang, X.,Krebs, J.,Tripathi, S.,Sakabe, N.,Sobreira, D.R.,Huang, S.C.,Rao, S.S.P.,Pruett, N.,Chauss, D.,Sadler, E.,Lopez, A.,Nobrega, M.A.,Aiden, E.L.,Asturias, F.J.,Casellas, R.; A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers.; Cell, 178:1145-1158.e20, 2019; PubMed: 31402173; DOI: 10.1016/j.cell.2019.07.011

実験手法

ELECTRON MICROSCOPY (4.02 Å)