6VXR

Structure of Maternal embryonic leucine zipper kinase bound to LDSM276

Summary for 6VXR

• Entry DOI: 10.2210/pdb6vxr/pdb
• Descriptor: Maternal embryonic leucine zipper kinase, (7R)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5H)-one, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: protein kinase, inhibitor, structural genomics, structural genomics consortium, sgc, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 39741.01

Authors

Counago, R.M.,Takarada, J.E.,dos Reis, C.V.,Gama, F.H.,Azevedo, H.,Mascarello, A.,Guimaraes, C.R.,Structural Genomics Consortium (SGC) (deposition date: 2020-02-24, release date: 2020-07-29, Last modification date: 2023-10-11)

• Primary citation: Counago, R.M.,Takarada, J.E.,dos Reis, C.V.,Guimaraes, C.R.,Azevedo, H.,Mascarello, A.,Gama, F.H.; Structure of Maternal embryonic leucine zipper kinase bound to LDSM276; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)