6VXR
Structure of Maternal embryonic leucine zipper kinase bound to LDSM276
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Maternal embryonic leucine zipper kinase | polymer | 339 | 39295.6 | 1 | UniProt (Q14680) Pfam (PF00069) Pfam (PF21594) | Homo sapiens (Human) | hMELK,Protein kinase Eg3,pEg3 kinase,Protein kinase PK38,hPK38,Tyrosine-protein kinase MELK |
| 2 | B (A) | (7R)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5H)-one | non-polymer | 383.4 | 1 | Chemie (F7D) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
A: 1 - 338 (UniProt: Q14680)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39295.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 445.4 | |
| All* | Total formula weight | 39741.0 |
