6VI4
Nanobody-Enabled Monitoring of Kappa Opioid Receptor States
Summary for 6VI4
Entry DOI | 10.2210/pdb6vi4/pdb |
Descriptor | Kappa opioid receptor, Nanobody 6, (3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, ... (4 entities in total) |
Functional Keywords | g protein-coupled opioid receptor, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 100409.22 |
Authors | Che, T.,Roth, B.L. (deposition date: 2020-01-11, release date: 2020-03-18, Last modification date: 2023-10-11) |
Primary citation | Che, T.,English, J.,Krumm, B.E.,Kim, K.,Pardon, E.,Olsen, R.H.J.,Wang, S.,Zhang, S.,Diberto, J.F.,Sciaky, N.,Carroll, F.I.,Steyaert, J.,Wacker, D.,Roth, B.L. Nanobody-enabled monitoring of kappa opioid receptor states. Nat Commun, 11:1145-1145, 2020 Cited by PubMed: 32123179DOI: 10.1038/s41467-020-14889-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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