6VGM

Crystal structure of DPO4 with 8-oxoadenine (oxoA) and dTTP*

Summary for 6VGM

• Entry DOI: 10.2210/pdb6vgm/pdb
• Descriptor: DNA polymerase IV, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), DNA (5'-D(*TP*CP*AP*TP*(A38)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... (6 entities in total)
• Functional Keywords: dpo4, y-family dna polymerase, translesion synthesis, transferase
• Biological source: Saccharolobus solfataricus; More
• Total number of polymer chains: 6
• Total formula weight: 98066.96

Authors

Jung, H.,Lee, S. (deposition date: 2020-01-08, release date: 2021-01-06, Last modification date: 2023-10-11)

• Primary citation: Jung, H.,Lee, S.; Promutagenic bypass of 7,8-dihydro-8-oxoadenine by translesion synthesis DNA polymerase Dpo4.; Biochem.J., 477:2859-2871, 2020; PubMed: 32686822; DOI: 10.1042/BCJ20200449

Experimental method

X-RAY DIFFRACTION (2.84 Å)