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6VEQ

Con-Ins G1 in complex with the human insulin microreceptor in turn in complex with Fv 83-7

Summary for 6VEQ
Entry DOI10.2210/pdb6veq/pdb
DescriptorCon-Ins G1a A chain, SULFATE ION, Con-Ins G1 B chain, ... (10 entities in total)
Functional Keywordstoxin
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains12
Total formula weight148156.97
Authors
Menting, J.G.,Chou, D.H.-C.,Lawrence, M.C.,Xiong, X. (deposition date: 2020-01-02, release date: 2020-06-03, Last modification date: 2023-11-15)
Primary citationXiong, X.,Menting, J.G.,Disotuar, M.M.,Smith, N.A.,Delaine, C.A.,Ghabash, G.,Agrawal, R.,Wang, X.,He, X.,Fisher, S.J.,MacRaild, C.A.,Norton, R.S.,Gajewiak, J.,Forbes, B.E.,Smith, B.J.,Safavi-Hemami, H.,Olivera, B.,Lawrence, M.C.,Chou, D.H.
A structurally minimized yet fully active insulin based on cone-snail venom insulin principles.
Nat.Struct.Mol.Biol., 27:615-624, 2020
Cited by
PubMed: 32483339
DOI: 10.1038/s41594-020-0430-8
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.25 Å)
Structure validation

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