6VEQ
Con-Ins G1 in complex with the human insulin microreceptor in turn in complex with Fv 83-7
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, G | Con-Ins G1a A chain | polymer | 20 | 2358.7 | 2 | UniProt (A0A0B5AC95) In PDB | Conus geographus | |
2 | B, H | Con-Ins G1 B chain | polymer | 23 | 2802.1 | 2 | UniProt (A0A0B5A8Q2) In PDB | Conus geographus | |
3 | E, K | Insulin receptor subunit alpha | polymer | 317 | 36231.8 | 2 | UniProt (P06213) Pfam (PF01030) Pfam (PF00757) In PDB | Homo sapiens (Human) | IR |
4 | F, L | Insulin receptor | polymer | 16 | 1922.1 | 2 | UniProt (P06213) In PDB | Homo sapiens | IR |
5 | C, I | Fv 83-7 heavy chain | polymer | 138 | 15058.7 | 2 | Mus musculus (Mouse) | ||
6 | D, J | Fv 83-7 light chain | polymer | 121 | 13367.9 | 2 | Mus musculus (Mouse) | ||
7 | M, O | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G81315DD) | |||
8 | N, P | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 2 | In PDB GlyTouCan (G32152BH) | |||
9 | E, K | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
10 | E, D, K | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) |
Sequence modifications
E, K: 1 - 310 (UniProt: P06213)
F, L: 704 - 719 (UniProt: P06213)
PDB | External Database | Details |
---|---|---|
His 144 | Tyr 171 | conflict |
Ser 311 | - | expression tag |
Ser 312 | - | expression tag |
Ser 313 | - | expression tag |
Leu 314 | - | expression tag |
Val 315 | - | expression tag |
Pro 316 | - | expression tag |
Arg 317 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Pro 718 | Lys 745 | conflict |
Ser 719 | Thr 746 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 143482.7 | |
Branched | Number of molecules | 4 |
Total formula weight | 2962.7 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 1711.5 | |
All* | Total formula weight | 148157.0 |