6V7I
Structure of KPC-2 bound to Vaborbactam at 1.25 A
Summary for 6V7I
Entry DOI | 10.2210/pdb6v7i/pdb |
Descriptor | Carbapenem-hydrolyzing beta-lactamase KPC, Vaborbactam, SULFATE ION, ... (5 entities in total) |
Functional Keywords | carbapenemase, boronate, beta-lactamase, inhibitor, hydrolase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 31580.11 |
Authors | Pemberton, O.A.,Chen, Y. (deposition date: 2019-12-08, release date: 2020-08-12, Last modification date: 2023-10-11) |
Primary citation | Pemberton, O.A.,Tsivkovski, R.,Totrov, M.,Lomovskaya, O.,Chen, Y. Structural Basis and Binding Kinetics of Vaborbactam in Class A beta-Lactamase Inhibition. Antimicrob.Agents Chemother., 64:-, 2020 Cited by PubMed: 32778546DOI: 10.1128/AAC.00398-20 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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