6V53

The crystal structure of the 2009 H1N1 PA endonuclease mutant I38T in complex with SJ000985494

Summary for 6V53

• Entry DOI: 10.2210/pdb6v53/pdb
• Related: 5vpt
• Descriptor: Polymerase acidic protein, benzyl (2S)-2-(4-{[2-(6-amino-9H-purin-9-yl)ethyl]carbamoyl}-5-hydroxy-6-oxo-1,6-dihydropyrimidin-2-yl)pyrrolidine-1-carboxylate, Hexa Vinylpyrrolidone K15, ... (6 entities in total)
• Functional Keywords: nuclease influenza inhibitor resistance, hydrolase, viral protein
• Biological source: Influenza A virus (A/Luxembourg/43/2009(H1N1)); More
• Total number of polymer chains: 1
• Total formula weight: 24626.67

Authors

Cuypers, M.G.,Slavish, P.J.,Rankovic, Z.,White, S.W. (deposition date: 2019-12-03, release date: 2020-12-09, Last modification date: 2023-10-11)

• Primary citation: Cuypers, M.G.,Slavish, P.J.,Rankovic, Z.,White, S.W.; The crystal structure of the 2009 H1N1 PA endonuclease mutant I38T in complex with SJ000985494; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)