6V0N
PRMT5 bound to PBM peptide from Riok1
Summary for 6V0N
Entry DOI | 10.2210/pdb6v0n/pdb |
Descriptor | Protein arginine N-methyltransferase 5, Methylosome protein 50, Riok1 PBM peptide, ... (5 entities in total) |
Functional Keywords | methylation, epigenetics, splicing, sdma, transferase-splicing complex, transferase/splicing |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 111222.55 |
Authors | McMIllan, B.J.,Raymond, D.D. (deposition date: 2019-11-19, release date: 2020-08-26, Last modification date: 2023-10-11) |
Primary citation | Mulvaney, K.M.,Blomquist, C.,Acharya, N.,Li, R.,Ranaghan, M.J.,O'Keefe, M.,Rodriguez, D.J.,Young, M.J.,Kesar, D.,Pal, D.,Stokes, M.,Nelson, A.J.,Jain, S.S.,Yang, A.,Mullin-Bernstein, Z.,Columbus, J.,Bozal, F.K.,Skepner, A.,Raymond, D.,LaRussa, S.,McKinney, D.C.,Freyzon, Y.,Baidi, Y.,Porter, D.,Aguirre, A.J.,Ianari, A.,McMillan, B.,Sellers, W.R. Molecular basis for substrate recruitment to the PRMT5 methylosome. Mol.Cell, 81:3481-, 2021 Cited by PubMed: 34358446DOI: 10.1016/j.molcel.2021.07.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.11 Å) |
Structure validation
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