6UZX
Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and UBP791
Summary for 6UZX
Entry DOI | 10.2210/pdb6uzx/pdb |
Descriptor | Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2A, GLYCEROL, ... (6 entities in total) |
Functional Keywords | nmdar, ligand-binding domain, antagonist, membrane protein |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 2 |
Total formula weight | 65908.21 |
Authors | Wang, J.X.,Furukawa, H. (deposition date: 2019-11-15, release date: 2020-01-29, Last modification date: 2023-10-11) |
Primary citation | Wang, J.X.,Irvine, M.W.,Burnell, E.S.,Sapkota, K.,Thatcher, R.J.,Li, M.,Simorowski, N.,Volianskis, A.,Collingridge, G.L.,Monaghan, D.T.,Jane, D.E.,Furukawa, H. Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors. Nat Commun, 11:423-423, 2020 Cited by PubMed: 31969570DOI: 10.1038/s41467-020-14321-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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