6UZT
Crystal Structure of RPTP alpha
Summary for 6UZT
Entry DOI | 10.2210/pdb6uzt/pdb |
Descriptor | Receptor-type tyrosine-protein phosphatase alpha (2 entities in total) |
Functional Keywords | protein tyrosine phosphatase, enzyme, hydrolase, alpha/beta protein, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 139220.27 |
Authors | Santelli, E.,Wen, Y.,Yang, S.,Svensson, M.N.D.,Stanford, S.M.,Bottini, N. (deposition date: 2019-11-15, release date: 2020-03-18, Last modification date: 2023-10-11) |
Primary citation | Wen, Y.,Yang, S.,Wakabayashi, K.,Svensson, M.N.D.,Stanford, S.M.,Santelli, E.,Bottini, N. RPTP alpha phosphatase activity is allosterically regulated by the membrane-distal catalytic domain. J.Biol.Chem., 295:4923-4936, 2020 Cited by PubMed: 32139509DOI: 10.1074/jbc.RA119.011808 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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