6UW6

Cryo-EM structure of the human TRPV3 K169A mutant determined in lipid nanodisc

Summary for 6UW6

• Entry DOI: 10.2210/pdb6uw6/pdb
• EMDB information: 20918
• Descriptor: Transient receptor potential cation channel subfamily V member 3, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate (2 entities in total)
• Functional Keywords: ion channel trpv3, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 377042.67

Authors

Deng, Z.,Yuan, P. (deposition date: 2019-11-04, release date: 2020-07-01, Last modification date: 2024-03-06)

• Primary citation: Deng, Z.,Maksaev, G.,Rau, M.,Xie, Z.,Hu, H.,Fitzpatrick, J.A.J.,Yuan, P.; Gating of human TRPV3 in a lipid bilayer.; Nat.Struct.Mol.Biol., 27:635-644, 2020; PubMed: 32572252; DOI: 10.1038/s41594-020-0428-2

Experimental method

ELECTRON MICROSCOPY (3.66 Å)