6UW6
Cryo-EM structure of the human TRPV3 K169A mutant determined in lipid nanodisc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel subfamily V member 3 | polymer | 790 | 90670.7 | 4 | UniProt (Q8NET8) Pfam (PF12796) Pfam (PF00023) Pfam (PF00520) | Homo sapiens (Human) | TrpV3,Vanilloid receptor-like 3,VRL-3 |
| 2 | E, F, G, H, I... (A, B, C, D) | [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | non-polymer | 718.0 | 20 | Chemie (6OU) |
Sequence modifications
A, B, C, D: 1 - 790 (UniProt: Q8NET8)
| PDB | External Database | Details |
|---|---|---|
| Val 25 | Ile 25 | variant |
| Ala 169 | Lys 169 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 362682.8 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 14359.9 | |
| All* | Total formula weight | 377042.7 |
