6US5

DNA polymerase I Large Fragment from Bacillus stearothermophilus with DNA template, 3'-amino primer, dGpNHpp analog, and Mn2+

Summary for 6US5

• Entry DOI: 10.2210/pdb6us5/pdb
• Related: 6UR2 6UR4 6UR9
• Descriptor: DNA polymerase I, DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*(C42))-3'), DNA (5'-D(*CP*AP*CP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... (7 entities in total)
• Functional Keywords: dna polymerase, 3'-amino terminal primer, gpnhpp, mn2+, replication-dna complex, replication/dna
• Biological source: Geobacillus stearothermophilus; More
• Total number of polymer chains: 6
• Total formula weight: 147295.01

Authors

Zhang, W.,Lelyveld, V.S.,Szostak, J.W. (deposition date: 2019-10-24, release date: 2020-03-18, Last modification date: 2023-10-11)

• Primary citation: Lelyveld, V.S.,Zhang, W.,Szostak, J.W.; Synthesis of phosphoramidate-linked DNA by a modified DNA polymerase.; Proc.Natl.Acad.Sci.USA, 117:7276-7283, 2020; PubMed: 32188786; DOI: 10.1073/pnas.1922400117

Experimental method

X-RAY DIFFRACTION (2.25 Å)