6URY

Crystal structure of ricin A chain in complex with inhibitor 9-oxo-4-fluorenecarboxamide

Summary for 6URY

Entry DOI	10.2210/pdb6ury/pdb
Descriptor	Ricin, 9-oxo-9H-fluorene-4-carboxamide, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	ricin a chain, rta, hydrolase, toxin, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Ricinus communis (Castor bean)
Total number of polymer chains	2
Total formula weight	62229.81
Authors	Harijan, R.K.,Li, X.P.,Bonanno, J.B.,Almo, S.C.,Tumer, N.E.,Schramm, V.L. (deposition date: 2019-10-24, release date: 2020-06-17, Last modification date: 2023-10-11)
Primary citation	Li, X.P.,Harijan, R.K.,Kahn, J.N.,Schramm, V.L.,Tumer, N.E. Small Molecule Inhibitors Targeting the Interaction of Ricin Toxin A Subunit with Ribosomes. Acs Infect Dis., 6:1894-1905, 2020 Cited by PubMed: 32428396 DOI: 10.1021/acsinfecdis.0c00127 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.54 Å)

Structure validation