Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0017148 | biological_process | negative regulation of translation |
| A | 0030598 | molecular_function | rRNA N-glycosylase activity |
| B | 0017148 | biological_process | negative regulation of translation |
| B | 0030598 | molecular_function | rRNA N-glycosylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue R6T A 301 |
| Chain | Residue |
| A | GLU146 |
| A | THR159 |
| A | THR159 |
| A | EDO305 |
| A | EDO305 |
| A | HOH443 |
| A | GLU146 |
| A | SER149 |
| A | SER149 |
| A | ALA150 |
| A | TYR153 |
| A | TYR153 |
| A | GLY158 |
| A | GLY158 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | GLY30 |
| A | THR33 |
| A | THR34 |
| A | HOH408 |
| A | HOH444 |
| A | HOH460 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | ILE8 |
| A | THR71 |
| A | HOH541 |
| A | HOH552 |
| B | THR190 |
| B | ARG196 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | PHE93 |
| A | HIS94 |
| A | GLY120 |
| A | GLY121 |
| A | ASN122 |
| A | EDO310 |
| A | EDO315 |
| A | HOH426 |
| A | HOH544 |
| A | HOH587 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | PRO143 |
| A | GLU146 |
| A | ALA147 |
| A | ARG166 |
| A | SER167 |
| A | ILE170 |
| A | R6T301 |
| A | R6T301 |
| A | HOH443 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | ARG31 |
| A | LEU32 |
| A | THR33 |
| A | THR34 |
| A | GLN55 |
| A | HOH492 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | THR116 |
| B | TYR115 |
| B | THR116 |
| B | PHE117 |
| B | CL306 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | GLU127 |
| A | HOH529 |
| B | HOH664 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 309 |
| Chain | Residue |
| A | TYR154 |
| A | SER155 |
| A | HOH611 |
| B | HIS94 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 310 |
| Chain | Residue |
| A | ARG56 |
| A | ASP75 |
| A | VAL82 |
| A | ASP100 |
| A | EDO304 |
| A | HOH426 |
| A | HOH453 |
| A | HOH525 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 311 |
| Chain | Residue |
| A | ARG234 |
| A | PHE240 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 312 |
| Chain | Residue |
| A | ILE1 |
| A | PRO52 |
| A | ILE53 |
| A | HOH437 |
| B | ALA36 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 313 |
| Chain | Residue |
| A | GLN19 |
| A | GLU220 |
| A | ARG258 |
| A | ALA260 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 314 |
| Chain | Residue |
| A | ALA66 |
| A | GLU67 |
| A | THR156 |
| A | HOH498 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 315 |
| Chain | Residue |
| A | ASN122 |
| A | EDO304 |
| A | HOH593 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 316 |
| Chain | Residue |
| A | GLN112 |
| A | HOH589 |
| B | ASN132 |
| B | ASN136 |
| B | HOH601 |
| B | HOH622 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 317 |
| Chain | Residue |
| A | PRO95 |
| A | ASN97 |
| A | GLN98 |
| A | HOH425 |
| site_id | AD9 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 318 |
| Chain | Residue |
| A | GLN128 |
| A | LEU129 |
| A | GLY131 |
| A | PRO162 |
| A | ARG197 |
| A | HOH566 |
| A | HOH651 |
| B | ARG125 |
| B | GLN128 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 319 |
| Chain | Residue |
| A | GLY120 |
| A | ASN122 |
| A | ARG125 |
| A | HOH585 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 320 |
| Chain | Residue |
| A | ARG114 |
| A | HOH509 |
| A | HOH734 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 321 |
| Chain | Residue |
| A | GLY15 |
| A | HIS65 |
| B | GLN98 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 322 |
| Chain | Residue |
| A | PHE108 |
| A | HOH655 |
| A | HOH725 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 323 |
| Chain | Residue |
| A | GLN160 |
| A | ARG197 |
| A | HOH565 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 324 |
| Chain | Residue |
| A | TYR123 |
| A | ASP124 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 325 |
| Chain | Residue |
| A | SER198 |
| A | ALA199 |
| A | HOH707 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 326 |
| Chain | Residue |
| A | ASN132 |
| A | LEU133 |
| A | ASN136 |
| site_id | AE9 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 327 |
| Chain | Residue |
| A | TYR243 |
| A | HOH422 |
| A | HOH486 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 328 |
| Chain | Residue |
| A | HIS106 |
| B | ARG234 |
| B | ARG235 |
| B | HOH594 |
| site_id | AF2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 301 |
| Chain | Residue |
| A | MET0 |
| B | GLY30 |
| B | THR33 |
| B | HOH406 |
| B | HOH408 |
| B | HOH430 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | GLU146 |
| B | ARG166 |
| B | SER167 |
| B | ILE170 |
| B | HOH433 |
| B | HOH547 |
| site_id | AF4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | TYR153 |
| B | GLY158 |
| B | HOH476 |
| B | HOH569 |
| site_id | AF5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | ASN222 |
| B | GLN223 |
| site_id | AF6 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 305 |
| Chain | Residue |
| B | ARG114 |
| B | HOH709 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 306 |
| Chain | Residue |
| A | ALA118 |
| A | EDO307 |
| B | ALA118 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 307 |
| Chain | Residue |
| B | PHE108 |
| B | HOH537 |
| B | HOH570 |
| B | HOH572 |
| site_id | AF9 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 308 |
| Chain | Residue |
| B | ASN132 |
| B | LEU133 |
| B | ASN136 |
| site_id | AG1 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 309 |
| Chain | Residue |
| B | GLY120 |
| B | ARG125 |
| B | HOH600 |
| site_id | AG2 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 310 |
Functional Information from PROSITE/UniProt
| site_id | PS00275 |
| Number of Residues | 17 |
| Details | SHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. IqMIsEAARFQyIEgeM |
| Chain | Residue | Details |
| A | ILE172-MET188 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Active site: {"evidences":[{"source":"UniProtKB","id":"P84531","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"8780513","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OBT","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000080","evidences":[{"source":"PubMed","id":"1368517","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; partial","featureId":"CAR_000081","evidences":[{"source":"PubMed","id":"1368517","evidenceCode":"ECO:0000269"}]} |
