6URQ

Complex structure of human poly-ADP-ribosyltransferase TNKS1 ARC2-ARC3 and P antigen family member 4 (PAGE4)

6URQ の概要

• エントリーDOI: 10.2210/pdb6urq/pdb
• 分子名称: Poly [ADP-ribose] polymerase tankyrase-1, P antigen family member 4, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: tnks, page4, tankyrase, parp, cancer-testis antigen, wnt signaling, transferase-transcription complex, transferase/transcription
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 92424.50

構造登録者

Zheng, Y.,Koirala, S.,Miller, D.,Potts, P.R. (登録日: 2019-10-24, 公開日: 2020-07-29, 最終更新日: 2023-10-11)

• 主引用文献: Koirala, S.,Klein, J.,Zheng, Y.,Glenn, N.O.,Eisemann, T.,Fon Tacer, K.,Miller, D.J.,Kulak, O.,Lu, M.,Finkelstein, D.B.,Neale, G.,Tillman, H.,Vogel, P.,Strand, D.W.,Lum, L.,Brautigam, C.A.,Pascal, J.M.,Clements, W.K.,Potts, P.R.; Tissue-Specific Regulation of the Wnt/ beta-Catenin Pathway by PAGE4 Inhibition of Tankyrase.; Cell Rep, 32:107922-107922, 2020; PubMed: 32698014; DOI: 10.1016/j.celrep.2020.107922

実験手法

X-RAY DIFFRACTION (2.05 Å)