6URH

Crystal structure of broadly neutralizing antibody AR3X in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain

6URH の概要

• エントリーDOI: 10.2210/pdb6urh/pdb
• 分子名称: HCV envelope glycoprotein E2, AR3X Heavy Chain, AR3X Light Chain, ... (9 entities in total)
• 機能のキーワード: hcv glycoprotein, broadly neutralizing antibodies, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Hepacivirus C; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 83121.19

構造登録者

Flyak, A.I.,Bjorkman, P.J. (登録日: 2019-10-23, 公開日: 2020-03-18, 最終更新日: 2023-10-11)

• 主引用文献: Flyak, A.I.,Ruiz, S.E.,Salas, J.,Rho, S.,Bailey, J.R.,Bjorkman, P.J.; An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein.; Elife, 9:-, 2020; PubMed: 32125272; DOI: 10.7554/eLife.53169

実験手法

X-RAY DIFFRACTION (2.2 Å)