6UQI

Crystal structure of Q38A human DNA polymerase eta bound with 8-oxoadenine (oxoA) and non-hydrolyzable dGTP analog (dGTP*)

Summary for 6UQI

• Entry DOI: 10.2210/pdb6uqi/pdb
• Descriptor: DNA polymerase eta, DNA (5'-D(*CP*AP*TP*(A38)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (6 entities in total)
• Functional Keywords: translesion synthesis, y-family dna polymerase, oxidative lesion, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 55265.75

Authors

Jung, H.,Lee, S. (deposition date: 2019-10-19, release date: 2020-10-28, Last modification date: 2023-10-11)

• Primary citation: Jung, H.,Lee, S.; Crystal structure of Q38A human DNA polymerase eta bound with 8-oxoadenine (oxoA) and non-hydrolyzable dGTP analog (dGTP*); To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)