6UPG

Crystal structure of Mycobacterium tuberculosis CYP121 in complex with cYF-4-OMe

Summary for 6UPG

Entry DOI	10.2210/pdb6upg/pdb
Descriptor	Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, (3~{S},6~{S})-3-[(4-hydroxyphenyl)methyl]-6-[(4-methoxyphenyl)methyl]piperazine-2,5-dione, ... (4 entities in total)
Functional Keywords	analog, c-c, unusual, p450, oxidoreductase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	44131.53
Authors	Nguyen, R.C.D.,Yang, Y.,Liu, A. (deposition date: 2019-10-17, release date: 2020-04-29, Last modification date: 2023-10-11)
Primary citation	Nguyen, R.C.,Yang, Y.,Davis, I.,Liu, A. Substrate-Assisted Hydroxylation and O-Demethylation in the Peroxidase-like Cytochrome P450 Enzyme CYP121 Acs Catalysis, 10:1628-1639, 2020 Cited by DOI: 10.1021/acscatal.9b04596 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.393 Å)

Structure validation