6UNQ
Kinase domain of ALK2-K493A with AMPPNP
Summary for 6UNQ
Entry DOI | 10.2210/pdb6unq/pdb |
Descriptor | Activin receptor type-1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | kinase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 38720.85 |
Authors | |
Primary citation | Agnew, C.,Ayaz, P.,Kashima, R.,Loving, H.S.,Ghatpande, P.,Kung, J.E.,Underbakke, E.S.,Shan, Y.,Shaw, D.E.,Hata, A.,Jura, N. Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization. Nat Commun, 12:4950-4950, 2021 Cited by PubMed: 34400635DOI: 10.1038/s41467-021-25248-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report