6UKT

Cryo-EM structure of mammalian Ric-8A:Galpha(i):nanobody complex

6UKT の概要

• エントリーDOI: 10.2210/pdb6ukt/pdb
• EMDBエントリー: 20812
• 分子名称: Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), Guanine nucleotide-binding protein G(i) subunit alpha-1, NB8109, ... (6 entities in total)
• 機能のキーワード: ric-8a, g protein, gef, signaling protein
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 150597.49

構造登録者

Mou, T.C.,Zhang, K.,Johnston, J.D.,Chiu, W.,Sprang, S.R. (登録日: 2019-10-05, 公開日: 2020-03-11)

• 主引用文献: McClelland, L.J.,Zhang, K.,Mou, T.C.,Johnston, J.,Yates-Hansen, C.,Li, S.,Thomas, C.J.,Doukov, T.I.,Triest, S.,Wohlkonig, A.,Tall, G.G.,Steyaert, J.,Chiu, W.,Sprang, S.R.; Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to G alpha i1.; Nat Commun, 11:1077-1077, 2020; PubMed: 32103024; DOI: 10.1038/s41467-020-14943-4

実験手法

ELECTRON MICROSCOPY (3.87 Å)