6UJ0

Unbound BACE2 mutant structure

Summary for 6UJ0

Entry DOI	10.2210/pdb6uj0/pdb
Descriptor	Beta-secretase 2, unidentified polypeptide (3 entities in total)
Functional Keywords	aspartic protease, peptide binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	100111.49
Authors	Yen, Y.C.,Ghosh, A.K.,Mesecar, A.D. (deposition date: 2019-10-01, release date: 2020-10-07, Last modification date: 2023-10-11)
Primary citation	Yen, Y.C.,Kammeyer, A.M.,Tirlangi, J.,Ghosh, A.K.,Mesecar, A.D. A Structure-Based Discovery Platform for BACE2 and the Development of Selective BACE Inhibitors. Acs Chem Neurosci, 12:581-588, 2021 Cited by PubMed: 33544569 DOI: 10.1021/acschemneuro.0c00629 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation