6UJ0
Unbound BACE2 mutant structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-secretase 2 | polymer | 460 | 49442.0 | 2 | UniProt (Q9Y5Z0) Pfam (PF00026) | Homo sapiens (Human) | Aspartic-like protease 56 kDa,Aspartyl protease 1,Asp 1,Beta-site amyloid precursor protein cleaving enzyme 2,Beta-site APP cleaving enzyme 2,Down region aspartic protease,DRAP,Memapsin-1,Membrane-associated aspartic protease 1,Theta-secretase |
| 2 | C, D (C, D) | unidentified polypeptide | polymer | 7 | 613.7 | 2 | Homo sapiens (Human) | ||
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 172 | Chemie (HOH) |
Sequence modifications
A, B: -61 - 398 (UniProt: Q9Y5Z0)
| PDB | External Database | Details |
|---|---|---|
| Ala 269 | Glu 331 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 100111.5 | |
| All* | Total formula weight | 100111.5 |
