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6UJ0

Unbound BACE2 mutant structure

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Beta-secretase 2polymer46049442.02UniProt (Q9Y5Z0)
Pfam (PF00026)
Homo sapiens (Human)Aspartic-like protease 56 kDa,Aspartyl protease 1,Asp 1,Beta-site amyloid precursor protein cleaving enzyme 2,Beta-site APP cleaving enzyme 2,Down region aspartic protease,DRAP,Memapsin-1,Membrane-associated aspartic protease 1,Theta-secretase
2C, D
(C, D)
unidentified polypeptidepolymer7613.72Homo sapiens (Human)
3E, F, G, H
(A, B, C, D)
waterwater18.0172Chemie (HOH)
Sequence modifications
A, B: -61 - 398 (UniProt: Q9Y5Z0)
PDBExternal DatabaseDetails
Ala 269Glu 331engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight100111.5
All*Total formula weight100111.5
*Water molecules are not included.

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PDB entries from 2025-10-29

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