6UIT

HIV-1 wild-type reverse transcriptase-DNA complex with dCTP

Summary for 6UIT

Entry DOI	10.2210/pdb6uit/pdb
Descriptor	p66 Reverse transcriptase/RNaseH, p51 Reverse transcriptase/RNaseH, DNA primer, ... (8 entities in total)
Functional Keywords	hiv-1 reverse transcriptase nrti polymerase dna complex, viral protein
Biological source	Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) More
Total number of polymer chains	4
Total formula weight	132858.48
Authors	Lansdon, E.B. (deposition date: 2019-10-01, release date: 2019-12-25, Last modification date: 2023-10-11)
Primary citation	Hung, M.,Tokarsky, E.J.,Lagpacan, L.,Zhang, L.,Suo, Z.,Lansdon, E.B. Elucidating molecular interactions ofL-nucleotides with HIV-1 reverse transcriptase and mechanism of M184V-caused drug resistance. Commun Biol, 2:469-469, 2019 Cited by PubMed: 31872074 DOI: 10.1038/s42003-019-0706-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.80607409399 Å)

Structure validation