6UIT
HIV-1 wild-type reverse transcriptase-DNA complex with dCTP
Summary for 6UIT
Entry DOI | 10.2210/pdb6uit/pdb |
Descriptor | p66 Reverse transcriptase/RNaseH, p51 Reverse transcriptase/RNaseH, DNA primer, ... (8 entities in total) |
Functional Keywords | hiv-1 reverse transcriptase nrti polymerase dna complex, viral protein |
Biological source | Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) More |
Total number of polymer chains | 4 |
Total formula weight | 132858.48 |
Authors | Lansdon, E.B. (deposition date: 2019-10-01, release date: 2019-12-25, Last modification date: 2023-10-11) |
Primary citation | Hung, M.,Tokarsky, E.J.,Lagpacan, L.,Zhang, L.,Suo, Z.,Lansdon, E.B. Elucidating molecular interactions ofL-nucleotides with HIV-1 reverse transcriptase and mechanism of M184V-caused drug resistance. Commun Biol, 2:469-469, 2019 Cited by PubMed: 31872074DOI: 10.1038/s42003-019-0706-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.80607409399 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)