6UGH

Cryo-EM structure of the apo form of human PRMT5:MEP50 complex at a resolution of 3.4 angstrom

Summary for 6UGH

• Entry DOI: 10.2210/pdb6ugh/pdb
• EMDB information: 20764 7137
• Descriptor: Protein arginine N-methyltransferase 5, Methylosome protein 50 (2 entities in total)
• Functional Keywords: prmt5, methyltransferase, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 114284.91

Authors

Zhou, W.,Yadav, G.P.,Jiang, Q.-X.,Li, C. (deposition date: 2019-09-26, release date: 2020-12-09, Last modification date: 2024-03-20)

• Primary citation: Zhou, W.,Yadav, G.P.,Jiang, Q.-X.,Li, C.; A 3.4-angstrom cryo-EM structure of the apo form of hu-man PRMT5:MEP50 complex reveals sequential catalysis of symmetric methyl transfer; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.4 Å)