6UEK

Structure of Urocanate Hydratase from Trypanosoma cruzi in complex with NAD+

Summary for 6UEK

Entry DOI	10.2210/pdb6uek/pdb
Descriptor	Urocanate hydratase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
Functional Keywords	chagas disease, urocanate hydratase, nad+, interdomain movement, lyase
Biological source	Trypanosoma cruzi
Total number of polymer chains	4
Total formula weight	305402.01
Authors	Boreiko, S.,Silva, M.,Melo, R.F.P.,Silber, A.M.,Iulek, J. (deposition date: 2019-09-21, release date: 2020-01-15, Last modification date: 2023-10-11)
Primary citation	Boreiko, S.,Silva, M.,de F P Melo, R.,Silber, A.M.,Iulek, J. Structure of Urocanate Hydratase from the protozoan Trypanosoma cruzi. Int.J.Biol.Macromol., 146:716-724, 2019 Cited by PubMed: 31843618 DOI: 10.1016/j.ijbiomac.2019.12.101 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.16 Å)

Structure validation