6UC3
Spectroscopic and structural characterization of a genetically encoded direct sensor for protein-ligand interactions
Summary for 6UC3
Entry DOI | 10.2210/pdb6uc3/pdb |
Descriptor | Streptavidin, BIOTIN (3 entities in total) |
Functional Keywords | unnatural amino acid, non-canonical amino acid, fluorescence, biosensor, small molecule biosensor, ligand detection, biotin binding protein |
Biological source | Streptomyces avidinii |
Total number of polymer chains | 2 |
Total formula weight | 29772.30 |
Authors | Mills, J.H.,Gleason, P.R.,Simmons, C.R.,Henderson, J.N.,Kartchner, B.K. (deposition date: 2019-09-13, release date: 2020-09-16, Last modification date: 2023-11-15) |
Primary citation | Gleason, P.R.,Kolbaba-Kartchner, B.,Henderson, J.N.,Stahl, E.P.,Simmons, C.R.,Mills, J.H. Structural Origins of Altered Spectroscopic Properties upon Ligand Binding in Proteins Containing a Fluorescent Noncanonical Amino Acid. Biochemistry, 60:2577-2585, 2021 Cited by PubMed: 34415744DOI: 10.1021/acs.biochem.1c00291 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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