6U3J
Structure of the 2-oxoadipate dehydrogenase DHTKD1
Summary for 6U3J
Entry DOI | 10.2210/pdb6u3j/pdb |
Descriptor | 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | lysine metabolism mitochondrial dehydrogenase, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 204599.84 |
Authors | Khamrui, S.,Lazarus, M.B. (deposition date: 2019-08-21, release date: 2020-07-22, Last modification date: 2023-10-11) |
Primary citation | Leandro, J.,Khamrui, S.,Wang, H.,Suebsuwong, C.,Nemeria, N.S.,Huynh, K.,Moustakim, M.,Secor, C.,Wang, M.,Dodatko, T.,Stauffer, B.,Wilson, C.G.,Yu, C.,Arkin, M.R.,Jordan, F.,Sanchez, R.,DeVita, R.J.,Lazarus, M.B.,Houten, S.M. Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex. Acs Chem.Biol., 15:2041-2047, 2020 Cited by PubMed: 32633484DOI: 10.1021/acschembio.0c00114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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