6U3J

Structure of the 2-oxoadipate dehydrogenase DHTKD1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial	polymer	904	101838.1	2	UniProt (Q96HY7) Pfam (PF00676) Pfam (PF02779) Pfam (PF16870)	Homo sapiens (Human)	Dehydrogenase E1 and transketolase domain-containing protein 1
2	C, F (A, B)	THIAMINE DIPHOSPHATE	non-polymer		425.3	2	Chemie (TPP)
3	D, E, G (A, B)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
4	H, I (A, B)	water	water		18.0	962	Chemie (HOH)

Sequence modifications

A, B: 25 - 919 (UniProt: Q96HY7)

PDB	External Database	Details
Met 23	-	initiating methionine
Gly 24	-	expression tag
His 920	-	expression tag
His 921	-	expression tag
His 922	-	expression tag
His 923	-	expression tag
His 924	-	expression tag
His 925	-	expression tag
His 926	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	203676.3
Non-Polymers*	Number of molecules	5
	Total formula weight	923.5
All*	Total formula weight	204599.8

*Water molecules are not included.