6U08

Double-stranded DNA-specific cytidine deaminase type VI secretion system effector and cognate immunity complex from Burkholderia cenocepacia

Summary for 6U08

Entry DOI	10.2210/pdb6u08/pdb
Descriptor	Double-stranded DNA-specific cytidine deaminase, DddI, ZINC ION, ... (4 entities in total)
Functional Keywords	type vi secretion system, toxin, immunity, deaminase
Biological source	Burkholderia cenocepacia More
Total number of polymer chains	8
Total formula weight	132094.68
Authors	Bosch, D.E.,de Moraes, M.M.H.,Mougous, J.D. (deposition date: 2019-08-13, release date: 2020-07-15, Last modification date: 2020-08-05)
Primary citation	Mok, B.Y.,de Moraes, M.H.,Zeng, J.,Bosch, D.E.,Kotrys, A.V.,Raguram, A.,Hsu, F.,Radey, M.C.,Peterson, S.B.,Mootha, V.K.,Mougous, J.D.,Liu, D.R. A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing. Nature, 583:631-637, 2020 Cited by PubMed: 32641830 DOI: 10.1038/s41586-020-2477-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.491 Å)

Structure validation